Hi,
I would say none of these.
First max lun size is 2 TB (-512B).
RDM would be great for vms having heavy ios.
So I would make it classic - some luns (max 2 TB) - so 1TB, 2, 2 (always -512B - I use always 2000GB) and let the vms place on them.
The big question is here the disk/raid layout - how many disks have you there?
Just my thoughts.
Reg
Christian