SQLFire does not provide a native Python driver today. We intend to provide access from Python, Perl among other languages but we don't have a firm date.
That said, Client-server protocol is DRDA - a common protocol used by Derby (SQLFire uses this) and several other IBM products. So, in theory, you should be able to access SQLFire servers using the DB2 runtime client. See http://www.ibm.com/developerworks/data/library/techarticle/dm-0505gibson/.
I understand this isn't the answer you are looking for, but, in case someone tries out this (or other) options I would be curious to know. thanks.